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The practice of nursing is a scientific process founded on a professional body of knowledge. It is a learned profession based on an understanding of the human condition across the lifespan and the relationship of a client with others and within the environment. The practice of nursing is an art dedicated to caring and to assisting clients by providing sustained, vigilant, and continuous care to those acutely or chronically ill. Nurses assist clients to attain or maintain optimal health, implementing a strategy of care to accomplish defined goals within the context of a client centered health care plan. Nursing is a dynamic discipline that increasingly involves more sophisticated knowledge, technologies and client care activities.


In North Carolina, Advanced Practice Registered Nurse (APRN) is an umbrella title for Registered Nurses who are, as defined in the North Carolina Administrative Code (21 NCAC 36.0120(6) ), as Nurse Practitioner, Nurse Anesthetist, Nurse-Midwife or Clinical Nurse Specialist.

  • Nurse Practitioner
    General Information; Laws & Rules; Prescribing; Back-up Supervising Physician; Collaborative Practice Guidelines; Compliance Review Materials; Continuing Education Requirements; Information at Practice Site; Refresher Course; Application Process; Position Statement; Frequently Asked Questions
  • Certified Registered Nurse Anesthetist
    General Information; Laws & Rules; Application Process
  • Certified Nurse Midwife
    General Information; Laws & Rules; Application Process
  • Clinical Nurse Specialist
    General Information; Laws & Rules; Application Process


Standards of Care for Opioid Prescribing
  • What Every Advanced Practice Registered Nurse Prescriber and Investigator Need to Know
  • Presentation by: Randall Steven Hudspeth, PhD, MBA, MS, APRN-CNP/CNS, FRE, FAANP


External Resources on Opioid Safety/Substance Use Disorder

Session Law 2015-241, mandated the creation of the North Carolina OPDAAC which is tasked with developing and implementing a strategic plan to Reduce Prescription Drug Abuse.

The campaign outlines real, actionable steps for the safe storage, use and disposal of pain medications, as well as resources for finding treatment and recovery support.

OPIOID Prescribing Alert

Provisions of the Strengthen Opioid Misuse Prevention (STOP) Act that limit initial prescriptions for acute pain to 5 days and postsurgical pain prescriptions to 7 days; became effective on January 1, 2018.

For more details, please see the following:

  1. Strengthen Opioid Misuse Prevention (NCBON)
  2. Controlled Substance Prescribing Information
  3. Prescribing-limits focused version of our STOP Act FAQs (NCMB)

Educational opportunities for meeting the requirements to apply for a medication-assisted therapy waiver

Last Changed 28-May-2019

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